program

Program Highlights

• Lectures and scientific abstracts on pathology, genetics, tumor microenvironment, therapeutics, clinical studies, quality of life and leading-edge research in cutaneous lymphomas
• Practice-changing workshops
• Debates and discussions on key controversies
• Interactive question and answer sessions
• Poster sessions
• Career and networking opportunities – discussions on research mentorship, industry relations and patient engagement

Credit © Helena Chu

6th World Congress of Cutaneous Lymphomas

Program Learning Objectives

At the conclusion of this congress, participants will be able to:

  1. Apply current diagnostic criteria and clinicopathologic correlations to accurately distinguish among major subtypes of cutaneous lymphomas, including mycosis fungoides, Sézary syndrome, and rarer primary cutaneous lymphoproliferative disorders.
  2. Integrate histopathologic, immunophenotypic, and molecular findings into staging and risk stratification of patients with cutaneous lymphomas to support evidence-based clinical decision-making.
  3. Select appropriate skin-directed and systemic treatment strategies for patients with cutaneous lymphoma based on disease subtype, stage, symptom burden, and prior treatment response.
  4. Evaluate emerging and novel therapies (including targeted agents, immunotherapies, and combination approaches) and determine how recent clinical trial data can be incorporated into real-world practice.
  5. Differentiate management approaches for early-stage versus advanced-stage disease, including indications for escalation of therapy and referral for specialized or multidisciplinary care.
  6. Recognize and manage treatment-related toxicities and quality-of-life issues, including pruritus, infections, and long-term therapy complications, to optimize patient outcomes.
  7. Apply standardized response assessment tools and follow-up strategies to monitor disease progression, treatment effectiveness, and relapse in patients with cutaneous lymphoma.
  8. Identify special clinical scenarios—such as pediatric disease, erythrodermic presentations, refractory disease, and comorbid conditions—and adapt management strategies accordingly.
  9. Incorporate multidisciplinary perspectives (dermatology, hematology/oncology, pathology, radiation oncology, and allied health) to improve diagnostic accuracy and coordinated care.

6th World Congress of Cutaneous Lymphomas

Invited Keynote Speakers

Thomas S. Kupper, MD
Chair Emeritus, Department of Dermatology, Brigham and Women’s Hospital
Chair, Department of Dermatology, Dana-Farber Cancer Institute
Thomas B. Fitzpatrick Professor, Harvard Medical School

Keynote Presentation: 40 Years of Research on Skin Immunity

Dr. Kupper was the founding Chair of the Department of Dermatology at Brigham and Women’s Hospital, where he led the department for more than 25 years.  He is chair at the Dana Farber Cancer Institute, and the Thomas B Fitzpatrick Professor of Dermatology at Harvard Medical School. He is the founder of the Cutaneous Oncology Disease Center and leads the Cutaneous Lymphoma Program at the Dana-Farber Cancer Center.  Dr. Kupper is an internationally known expert in the treatment and care of Cutaneous Lymphomas. He is also a respected teacher and mentor, and many of his trainees have gone on to become Department Chairs, Chiefs, or academic faculty around the country and the world.  Dr. Kupper’s research has been continuously funded by the National Institutes of Health for 35 years and is focused on: 1) T cell vaccine biology, 2) T cell immunobiology, including T cell subsets resident to tissue (TRM), and 3) Cancer immunobiology including immunotherapy. His current work is supported by the National Institutes for Allergy and Infectious Diseases, the National Institute for Arthritis, Musculoskeletal and Skin Diseases and the National Institute for Cancer. He has previously been funded by a MERIT award from the NIAID, the first Specialized Program in Research Excellence (SPORE) in Skin Cancer (NCI), and a Transformative Research Award from the NIH Office of the Director. He has served on multiple NIH study sections from 1991 to present.   He has received numerous awards, including the SID William Montagna Award and Kligman-Frost Leadership Award, the JSID Tanioku Kihei Award, the ESDR Rene Touraine Award, the AAD Marion Sulzberger Award, and is an honorary member of the Korean, Japanese, Swiss, and Austrian Societies for Investigative Dermatology. He has been elected to the American Society for Clinical Investigation, the American Dermatologic Association, the American Association of Physicians and is a Fellow of the American Association of Arts and Sciences.

 

Jason Hipp, MD, PhD
Chief Digital Innovation Officer for Mayo Collaborative Services
Medical Director for Biopharma Diagnostics

Keynote Presentation: Advances in Computational/Digital Pathology and AI in the diagnosis of Cancer and Prediction of Prognosis

Jason D. Hipp, MD, PhD, is a board-certified anatomic pathologist and physician-scientist with expertise in computational pathology, digital pathology, and artificial intelligence in diagnostic medicine. He completed his pathology residency at the National Institutes of Health and a clinical informatics fellowship at the University of Michigan. He previously founded and served as Chair of Computational Pathology and AI at Mayo Clinic and has also held leadership roles at Google/Verily and AstraZeneca. He is currently Founder and CEO of JDH Consulting, where he advises emerging companies in pathology and diagnostics and supports innovation in digital and AI-enabled technologies for the field. Dr. Hipp’s work has focused on the development and translation of machine learning, image analysis, and digital technologies in pathology, particularly in biomarker development, translational research, and clinical implementation. He is recognized for bridging pathology, informatics, and emerging technology across academic and industry settings.

Program at a glance

Detailed Program – at Apr  20, 2026

Wednesday, June 24

 

 13:00–14:00

USCLC Board Meeting [by invitation]
McGill
 14:00–15:30 ISCL Board Meeting [by invitation]
Ramzay
15:00-18:00 Registration opens
Montreal Ballroom Foyer
 
 15:30–16:30 EORTC Board Meeting [by invitation]
McGill
 
 16:30–18:30

 19:00–21:30

ISCL Board of Directors Dinner [by invitation]
Offsite
Thursday, June 25
06:30–17:00 REGISTRATION
 07:00–08:00 CONTINENTAL BREAKFAST AND POSTER VIEWING IN EXHIBIT HALL
Grande Place (8th Floor)
08:15–08:30 Welcome & Announcements
Montreal Ballroom
 
     
08:35 – 10:00

Session 1A – New biomarkers for predicting outcome in CTCL
Montreal Ballroom

Chair: Steven Horwitz
Co-Chairs: Maxime Battistella, Alison Moskowitz

Session 1B – From Novel Topicals to Real-world Outcomes
Fortifications Ballroom

Chair: Tomomitsu Miyagaki
Co-Chairs: Antonio Cozzio, Julia Dai

Session Learning Objectives:

At the end of this session, participants will be able to: 

1. Apply new biomarkers to understanding of prognosis in CTCL
2. Clarify relationship of dupilumab and risk of CTCL progression

At the end of this session, participants will be able to: 

1. Apply emerging clinical trial data on novel topical therapies to the management of early-stage cutaneous T-cell lymphoma.
2. Analyze long-term clinical trajectories and relapse patterns in indolent B-cell lymphomas and CD4+ LPD based on large-scale cohort studies and real-world evidence.
3. Identify key risk factors and complications, such as second primary malignancies and folliculotropism, to improve long-term survivorship care.

08:35 Introduction – Steven Horwitz Introduction – Tomomitsu Miyagaki
08:40 Evaluation of TRBC1 immunohistochemistry versus high-throughput sequencing of TCRB gene for clonality assessment in cutaneous T-cell lymphomas
Andy Li, Service de Dermatologie, Hôpital Saint-Louis, APHP, France
Interim Results for FLASH2: A Confirmatory Phase 3 Study of Topical HyBryte™ Activated by Visible Light for Cutaneous T-Cell Lymphoma
Ellen J. Kim, Perelman School of Medicine at the University of Pennsylvania, USA
08:50 Unraveling the nature of T-cell clones of uncertain significance in cutaneous T-cell lymphomas
Safa Najidh, Stanford University, Palo Alto, USA
A pilot study to assess safety and efficacy of tofacitinib 2% cream in the treatment of early-stage mycosis fungoides
Julia Dai, University of Texas MD Anderson Cancer Center, USA
09:00 The Genomic Landscape of Mycosis Fungoides: Therapy-Associated UV Mutagenesis and Oncogenic JUNB A282V Mutation
Pan Lai, Peking University First Hospital, China
Treatment Outcomes and Frequent Relapsers in Primary Cutaneous Indolent B-Cell Lymphomas: A 213-Patient Single-Center Cohort Study
Silvia Alberti-Violetti, University of Milan, Italy
09:10 Distinct Molecular Signatures as Predictors of Early Mortality in Advanced Mycosis Fungoides
Pablo L. Ortiz-Romero, Hospital Universitario 12 de Octubre, Spain
Folliculotropism and Infection-Associated Outcomes in Cutaneous T-Cell Lymphoma
Toan Bui, Johns Hopkins University, USA
09:20 Head and Neck Lesions as Sentinel Clinical Features of Dupilumab-Associated Cutaneous T Cell Lymphoma
Yu Xiao, Peking University First Hospital, China
The risk of developing second primary malignancies in patients with cutaneous lymphomas
Lauren Banner, Thomas Jefferson University, USA
09:30 Dupilumab Accelerates T-Cell Lymphoma via A20-Deficient NF-kB Signaling and STAT3/5 Amplification
Mingjia Li, Peking University First Hospital, China
Real-world outcomes of primary cutaneous CD4⁺ small/medium T-cell lymphoproliferative disorder in a UK supra-regional cutaneous lymphoma centre
Neenu Sebastian, University Hospitals Birmingham NHS Foundation Trust, United Kingdom
09:40 Loss of fibroblast interaction with malignant T-cell clones is associated with aggressive CTCL behavior across CD4+, CD8+ and TCR-γδ+ malignant phenotypes
Abigail Fleischli, Department of Dermatology, Icahn School of Medicine at Mount Sinai, USA
Clinical Outcomes in Primary Cutaneous Peripheral T-cell Lymphoma, Not Otherwise Specified
Robert Stuver, Memorial Sloan Kettering Cancer Center, New York, USA
09:50 Q&A / Panel Discussion Q&A / Panel Discussion
 10:00-10:40 MORNING BREAK AND POSTER VIEWING IN EXHIBIT HALL
Grande Place (8th Floor)
10:40 – 12:00

Session 2 – Risk, Disparities, and Prognostic Determinants in Cutaneous T-Cell Lymphoma
Montreal Ballroom

Chair: Larisa Geskin
Co-Chairs: Pamela B. Allen, Sima Rozati

Learning Objectives:

At the end of this session, participants will be able to: 

  1. Identify clinical and biologic high-risk features in early-stage mycosis fungoides and Sézary syndrome.
  2. Analyze racial, ethnic, and socioeconomic disparities affecting diagnosis, disease severity, and outcomes in CTCL.
    3. Apply emerging diagnostic and biologic tools to improve risk stratification and promote equitable care in patients with CTCL.
10:40 Introduction – Larisa Geskin
10:45 Identifying High-Risk Early-Stage Mycosis Fungoides: Prognostic Insights from the PROCLIPI Cohort
Julia J. Scarisbrick, University Hospitals Birmingham NHS Foundation Trust, United Kingdom
10:55 Racial Differences in Prognosis in Mycosis Fungoides and Sézary Syndrome: Analysis from the BEACON (Building an Equitable and Collaborative Oncology Network)-CTCL Cohort
Pamela B. Allen, Winship Cancer Institute of Emory University, USA
11:05 Colour Lines in Cancer? Exploring race as determinant of Cutaneous T-Cell Lymphoma outcomes, using the global PROCLIPI cohort
Abraham E. Bashir, University Hospitals Birmingham NHS Foundation Trust, United Kingdom
11:15 Racial and Ethnic Disparities in T-Cell Receptor Beta Repertoire in Cutaneous T-Cell Lymphoma
Liliana L. Crisan, City of Hope Comprehensive Cancer and Beckman Research Institute, USA
11:25 Bridging Racial Disparities in Mycosis Fungoides Diagnosis Through Dermoscopy
Hadar K. Shimshon, Downstate University of New York Downstate Health Sciences University, USA
11:35 Mycosis Fungoides in the Pediatric Population in Chile: A Retrospective Study
Rocío Millán, Pontificia Universidad Católica de Chile, Santiago, Chile
11:45 Area Deprivation and Disease Severity in Adult Patients with Cutaneous T-Cell Lymphoma
Kofi Owusu-Ansah, University of Wisconsin, USA
11:55 Q&A / Panel Discussion
12:00–13:15

Accredited Symposium: The Importance of Durability of Response in Managing CTCL
Co-developed with Therakos LLC
Fortifications Ballroom

Lunch served

LUNCH AND POSTER VIEWING IN EXHIBIT HALL
Grande Place (8th Floor)
13:30-14:20

Plenary: Herschel S. Zackeim Lectureship
40 Years of Research on Skin Immunity Thomas Kupper
Montreal Ballroom

Chairs: Julia Scarisbrick, Steven Horwitz

   
14:30 – 15:50

14:30 – 15:50

Session 3A – T cells Gone Rogue: Single-Cell, Spatial, and Molecular Frontiers in CTCL
Montreal Ballroom

Chair: Joan Guitart
Co-Chairs: Adele de Masson, Robert Gniadecki

14:30 – 15:30

Session 3B – Optimizing Mogamulizumab Therapy in Cutaneous T-Cell Lymphomas: Real-World Evidence, Safety, and Long Term Outcomes
Fortifications Ballroom

Chair: Pietro Quaglino
Co-Chairs: Barbara Pro, Kevin Imrie, Shamir Geller

Learning Objectives:

At the end of this session, participants will be able to:

1. Describe the lesion-specific immune, stromal, and microbiomic landscapes of Mycosis Fungoides as revealed by single-cell proteomic, transcriptomic, and multi-omics approaches.
2. Integrate emerging data on T-cell clonal dynamics, checkpoint-dominated microenvironments, and immunosuppressive mechanisms to better understand disease progression and treatment response in CTCL.
3. Apply novel biomarkers and AI-based tools — including deep-learning T-cell recognition and molecular profiling of treatment-exposed lesions — to inform prognosis and therapeutic decision-making in Mycosis Fungoides.

At the end of this session, participants will be able to:

 1. Evaluate real-world and on the effectiveness of mogamulizumab in patients with mycosis fungoides and Sézary syndrome, including comparative outcomes versus clinical trial evidence and standard therapies.
2. Assess management strategies associated with mogamulizumab treatment, including retreatment following adverse events such as drug-related rash.
3. Interpret long-term outcomes and treatment sequencing strategies, including discontinuation and retreatment approaches, to inform clinical decision-making in relapsed or refractory disease.

14:30 Introduction – Joan Guitart Introduction – Pietro Quaglino
14:35 Single-cell proteomic and transcriptomic profiling of lesion-specific aberrant T cell states and checkpoint-dominated microenvironment of Mycosis Fungoides
Eleni-Kyriaki Vetsika, Department of Basic and Clinical Sciences, Medical School, University of Nicosia, UNIC Athens, Greece
Real-world use of Mogamulizumab: final analysis of the “FIL-MOGA” study by the Italian Lymphoma Foundation (FIL)
Gabriele Roccuzzo, Department of Medical Sciences, Section of Dermbritology, University of Turin, Italy
14:45 Deep-learning based T-cell Recognition and Automated Clone Estimation in early-stage Mycosis Fungoides: a proof of concept study (TRACE-MF)
Pieter A. Valkema, Leiden University Medical Center, Netherlands
Patients with Mogamulizumab-associated rash can be safely retreated with Mogamulizumab with durable remissions: A single center experience
Amy Liao, Washington University School of Medicine, USA
14:55 Single-cell profiling of advanced-stage mycosis fungoides reveals distinct immune and stromal responses in tumor versus erythrodermic lesions
Patrick Brunner, Department of Dermatology, Icahn School of Medicine at Mount Sinai, USA
“Moga-Stop” Study:  extended follow-up of patients with Sézary syndrome treated with mogamulizumab after treatment discontinuation, excluding for progression
Marie Beylot-Barry, CHU Bordeaux, France
15:05 Integrated Transcriptomic and Microbiomic Profiling of Keratinocytes in Erythrodermic Cutaneous T-cell Lymphoma Identifies Distinct Epidermal-microbial Patterns
Katherine De Jong, Northwestern University, USA
Overall survival in patients with mycosis fungoides or Sézary syndrome in Denmark: comparative effectiveness of mogamulizumab versus standard of care
Lena Specht, Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark
15:15 The Role of CD84 (SLAMF5) in the Immunosuppressive Tumor Microenvironment of CTCL
Laura C. Schultz, Division of Dermatology, City of Hope, USA
Outcomes in relapsed/refractory mycosis fungoides or Sézary syndrome from the MAVORIC trial mogamulizumab arm versus a real-world Australian cohort receiving vorinostat
H. Miles Prince, Peter MacCallum Cancer Centre, Australia
15:25 Lesion-specific immune and clonal reprogramming drives Chlormethine gel response and treatment-associated dermatitis in Mycosis Fungoides
Evangelia Papadavid, Centre of Excellence for Rare Diseases-Cutaneous Lymphoma, ERN-EuroBloodNet, Second Department of Dermatology and Venereal Diseases, Attikon University General Hospital, National and Kapodistrian University of Athens, Greece
15:25 – 15:30 – Q&A / Panel Discussion
15:35 Molecular analysis of irradiated cutaneous T-cell lymphoma tumors suggests markers associated with response and risk of recurrence
Eleanor Ostroff, Department of Dermatology, Northwestern University Feinberg School of Medicine, USA

15:40 – 17:20

Session 4B – Integrating immune profiling with genomics to predict therapy response
Fortifications Ballroom

Chair: Christiane Querfeld
Co-Chairs: Alejandro Gru, Denis Miyashiro

At the end of this session, participants will be able to:

1. Describe how immune profiling of blood and skin informs disease biology and treatment response in CTCL.
2. Integrate genomic and clonality-based biomarkers into assessment of disease burden and therapeutic monitoring.
3. Apply emerging biomarker strategies to predict and evaluate response to mogamulizumab and other targeted therapies in CTCL.

 

15:45 Q&A / Panel Discussion 15:40 Introduction – Christiane Querfeld
16:00 – 17:20

Session 4A – Contemporary Advances in Cutaneous T-Cell Lymphomas’. New Frontiers in Cutaneous Lymphoma Diagnosis and Prognosis
Montreal Ballroom

Chair: Rudolf Stadler
Co-Chairs: Neda Nikbakht, Swami Iyer

15:45 – Functional Immune States of Blood and Skin Microenvironment Predict Mogamulizumab Response in Sézary Syndrome
Hélène Moins-Teisserenc, IRSL-Université Paris Cité, France
Learning Objectives

At the end of this session, participants will be able to:

1. Apply recent clinico-pathological and prognostic insights (e.g. lesional BSA thresholds, TFH phenotype, co-occurring lymphomas) to refine the diagnosis and risk stratification of cutaneous T-cell lymphomas in daily practice.
2. Integrate emerging tools, such as multiparameter flow cytometry, digital whole-slide image analysis and targeted genomics, to improve the classification and monitoring of primary cutaneous lymphomas.
3. Clarify how novel clinical entities and ‘borderline’ presentations beyond classical mycosis fungoides impact therapeutic decision-making and recommendations for patient follow-up.

15:55 – Targeted sequencing in patients with relapsed/refractory mycosis fungoides or Sézary syndrome treated with mogamulizumab in the MOGA-2MG-Q4W clinical trial
Christiane Querfeld, City of Hope National Medical Center, Beckman Research Institute, USA
16:00 Introduction – Rudolf Stadler
16:05 Presentation with confluent erythema not reaching 80% body surface area is associated with advanced stage disease and has worse outcome than classical MF in the early stages
Julia J. Scarisbrick, University Hospitals Birmingham NHS Foundation Trust, United Kingdom
Rapid and Durable Blood Remission in CTCL Using Mogamulizumab: B2 as a Surrogate Marker
Yenny Angela, University Clinic of Dermatology, Venerology, Allergology und Phlebology  Skincancer Center Johannes Wesling Medical Center, Ruhr University Bochum, Germany
16:15 Cutaneous flow cytometry: 10 years of experience from a single center
Emmanuela Guenova, Department of Translational Immunodermatology, Kepler University Hospital, Johannes Kepler University, Austria
Distinct genomic profiling of folliculotropic mycosis fungoides: integrated data of whole genome sequencing and single-cell spatial transcriptomics
Woo Jin Lee, Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Korea
16:25 Reproducible Cohort Generation and Whole-Slide Learning for Cutaneous T-Cell Lymphoma and Related Lymphoproliferative Disorders
Melissa Pulitzer, Memorial Sloan Kettering Cancer Center, USA
Non-JAK-Family Gene Fusions in Cutaneous T-cell Lymphoma Highlights Genetic Diversity and Potential Therapeutic Targets
Haiming Tang, Memorial Sloan Kettering Cancer Center, USA
16:35 Investigating the Genetic Landscape of Primary Cutaneous Lymphomas and Lymphoproliferative Disorders with T Follicular Helper Cell Phenotype (PCL-TFH)
Ziba Rahbar, Brigham and Woman’s Hospital, Harvard Medical School, USA
Evaluation of TRBC1-based Clonality to Quantitate Blood Involvement in Cutaneous T Cell Lymphoma
Katherine De Jong, Northwestern University, USA
16:45 Co-occurring Chronic Lymphocytic Leukemia in Mycosis Fungoides/Sézary Syndrome: Retrospective Analysis
Julia Dai, Department of Dermatology, The University of Texas MD Anderson Cancer Center, USA
Characterization of adult T-cell leukemia/lymphoma patients with specific skin lesions in a tertiary dermatological service in Brazil
Denis Miyashiro, Department of Dermatology, University of São Paulo Medical School, Brazil
16:55 Non-alpha/beta T-cell lymphoma: a single Centre experience on gamma/delta and TCR-silent subsets
Giorgio Alberto Croci, University of Milan, Italy
Baseline macrophage states determine immune reprogramming trajectories and clinical response to extracorporeal photopheresis in Sézary syndrome
Oleg Akilov, University of Pittsburg School of Medicine, USA
17:05 Mycosis fungoides with a gamma-delta immunophenotype: do they differ from epidermotropic primary cutaneous gamma-delta T-cell lymphoma?
Eleanor B. Ostroff, Department of Dermatology, Northwestern University Feinberg School of Medicine, USA
Molecular-based Reconsideration of Classification of Primary Cutaneous CD30-positive Lymphoproliferative Disorders
Yamato Suemitsu, Memorial Sloan Kettering Cancer Center, New York, USA
17:15 Q&A / Panel Discussion Q&A / Panel Discussion
17:30–18:30

POSTER SESSION WALK IN EXHIBIT HALL
Grande Place (8th Floor)

Primary Chair and Poster Walk Leader: Paula Enz

18:00–20:00 WELCOME RECEPTION
Grande Place (8th Floor)

 

Friday, June 26
06:30–17:00 REGISTRATION
 07:00–08:00 CONTINENTAL BREAKFAST AND POSTER VIEWING IN EXHIBIT HALL
Grande Place (8th Floor)
08:15-09:00

Plenary / Invited Speaker: Advances in Computational/Digital Pathology and AI in the Diagnosis of Cancer and Prediction of Prognosis Jason Hipp
Montreal Ballroom

Chairs: Steven Horwitz, Julia Scarisbrick

   
09:05 – 10:15

Session 5 – Cutaneous Lymphoma International Consortium: Together we can
Montreal Ballroom

Chair: Youn Kim
Co-Chairs: Marie Beylot-Barry, Rein Willemze

Learning Objectives At the end of this session, participants will be able to:
1. Appreciate that international collaborations are feasible and productive in generating large datasets in rare lymphomas
2. Recognize meaningful prognostic factors and treatment profiles and impact in CTCL utilizing international collective data

09:05

Introduction – Youn Kim

09:10

Building on CLIPI: Deeper Dive into Advanced Stage Subset
Youn Kim, Stanford University, USA

09:30

Treatment patterns in early-stage Mycosis Fungoides: a 10-Year update from the PROCLIPI study
Gabriele Roccuzzo, Department of Medical Sciences, Section of Dermatology, University of Turin, Italy

09:40

Navigating Therapeutic Complexity in Advanced-Stage MF/SS: Real-World Insights from the PROCLIPI Study Abraham E. Bashir, University Hospitals Birmingham NHS Foundation Trust, United Kingdom

09:50

Blood Tumor Burden Refines Prognostication: Validation of PROCLIPI for Advanced Cutaneous Lymphoma in a Chinese Cohort
Zhuojing Chen, Peking University First Hospital, China

10:00

How Big Is Big Enough? The Potential for Imaging-derived Quantitative Thresholds for Identifying N3 Nodal Disease in CTCL using PROCLIPI
Abraham E. Bashir, University Hospitals Birmingham NHS Foundation Trust, United Kingdom

10:10

Q&A / Panel Discussion

 10:15 – 10:55

 

MORNING BREAK AND POSTER VIEWING IN EXHIBIT HALL
Grande Place (8th Floor)
10:55 – 12:15

Session 6 – Novel Targets for CTCL Treatments
Montreal Ballroom

Chair: Martine Bagot
Co-Chairs: Michael Khodadoust, Auris Huen

Learning Objectives

At the end of this session, participants will be able to:

1. Identify and validate novel targets for the treatment of cutaneous T cell lymphoma.
2. Clarify the use of new treatments.

10:55

Introduction – Martine Bagot

11:00

Nivolumab with duvelisib leads to repeated immune-mediated toxicities in cutaneous T-cell lymphoma (CTCL): Clinical results of ETCTN Study 10347
Neha Mehta-Shah, Washington University in St. Louis, USA

11:10

Targeting TNFR2 with BI-1808: Immune Activation and Promising Responses in Advanced T-Cell Lymphomas – Stefan Barta, University of Pennsylvania Hospital, USA

11:20

Dupilumab Use in Atopic Dermatitis When Cutaneous Lymphoma Is Suspected: Consensus Recommendations from the EORTC Cutaneous Lymphoma Task Force
Emmanuella Guenova, Department of Translational Immunodermatology, Kepler University Hospital, Johannes Kepler University, Linz, Austria, Austria

11:30

Updated Clinical Data from the Phase 1 Study of Dibotatug (DR-01), a Non-Fucosylated Anti-CD94 Antibody in Patients with Relapsed/Refractory Cytotoxic T/NK cell Lymphomas
Swaminathan Iyer, MD Anderson Cancer Center, USA

11:40

Mycosis fungoides-exosomes mediate reprogramming of tumor-associated macrophages via a novel mechanism of CD47- SIRPα checkpoint interaction
Lilach Moyal, Rabin Medical Center and Tel-Aviv University, Israel

11:50

Preliminary results in a First-in-Human Trial of ST-001 nanoFenretinide in Previously Treated Cutaneous T-cell Lymphoma
Oleg Akilov, University of Pittsburg School of Medicine, USA

12:00

Cutaneous outcomes associated with nemolizumab use in patients with cutaneous T-cell lymphoma: a case series Krithika Nayudu, Medical College of Georgia, USA

12:10

Q&A / Panel Discussion

12:15 – 12:30

Welcome & Award Session
Montreal Ballroom

Chair: Julia Scarisbrick

* Special Award

* Lifetime Achievement Award 1

* Lifetime Achievement Award 2

12:30–13:55 LUNCH AND POSTER VIEWING IN EXHIBIT HALL
Grande Place (8th Floor)
12:40-13:55

Accredited Symposium:  Bridging the gap: Advancing diagnosis and management of CTCL through collaborative multidisciplinary care
Co-developed with Kyowa Kirin
Fortifications Ballroom

Lunch served

Learning Objectives:

By the end of this symposium, participants will be able to:

  • Recognize suspected CTCL by identifying diagnostic challenges and interpret the clinical and histopathological features of MF and SS using TNMB staging and diagnostic tools.
  • Outline effective referral pathways for suspected CTCL, enabling timely multidisciplinary collaboration while incorporating patient perspectives.
  • Apply multidisciplinary insights to assess disease and patient characteristics that inform CTCL management and treatment decisions.
14:05 – 15:20

Session 7A – Young Investigators Presentations: Risk, Disparities, and Disease Behavior in Cutaneous Lymphomas
Montreal Ballroom 

Chair: Oleg Akilov
Co-Chairs: Jade Cury Martins, Montserrat Molgo

Session 7B – “The Great Transformation”: LCT and predicting CTCL outcomes
Fortifications Ballroom

Chair: Yang Wang
Co-Chairs: Gizelle Popradi, Philippe Lefrancois

Learning Objectives:

At the end of this session, participants will be able to:

1.  Describe epidemiologic risks and secondary malignancy patterns in patients with cutaneous lymphomas.
2.  Recognize biologic and clinical factors, including microbial influences and phenotype, that contribute to disease severity and heterogeneity.
3.  Interpret prognostic indicators across CTCL and related entities, including extracutaneous progression and transplant-related outcomes.

At the end of this session, participants will be a able to:

1. Describe clinical indicators of poor outcome and progression in CTCL
2. Define the clinical and molecular features of LCT

14:05

Introduction – Oleg Akilov Introduction – Yang Wang

14:10

Risk of melanoma skin cancer among patients with mycosis fungoides and Sézary syndrome. A Swedish nationwide population-based cohort study.
Karolina Wojewoda, Department Dermatology and Venereology, University of Gothenburg, Sweden

Understanding The Molecular Triggers Of Cutaneous T-Cell Lymphoma (Mycosis Fungoides) Progression
Fabio Ianelli, Division of Hematopathology, IEO European Institute of Oncology IRCCS, Italy

 

14:20

Staphylococcal Hemolysins Associated with Racial Disparities and Increased Clinical Severity in Cutaneous T-Cell Lymphoma
Amy S. Kaku, Emory University School of Medicine, Department of Dermatology, USA
Large Cell Transformation in Mycosis Fungoides/Sezary Syndrome: Contemporary Outcomes, Predictors, and Disparities Signal from the U.S. BEACON-CTCL Cohort  Haris Qureshi, Yale School of Medicine, USA

14:30

Primary Cutaneous Marginal Zone Lymphoma developing extracutaneous disease: an European Organisation For Research And Treatment Cutaneous Lymphoma Tumour Group study.
Lindi Korpelshoek, Department of Dermatology, Leiden University Medical Center, Netherlands
International study of mycosis fungoides with large-cell transformation confirms poor outcome and reveals heterogeneity in presentation, treatment and prognosis
Belinda A. Campbell, Peter MacCallum Cancer Centre, Australia

14:40

Disease status at HSCT, including skin-limited disease, and survival in BPDCN: A retrospective, multicenter cohort study of the EORTC, Cutaneous Lymphoma Tumour Group
Christoph Iselin, Department of Dermatology, Lausanne University Hospital and Faculty of Biology and Medicine, University of Lausanne, Switzerland
Overall Survival in Transformed Mycosis Fungoides and Sezary Syndrome
Rishabh Lohray, Baylor College of Medicine, USA

14:50

Characteristics and outcomes of cutaneous T-cell lymphoma with gamma-delta phenotype: A single-center case series
Stephanie K. Lin, Department of Dermatology, Hospital of the University of Pennsylvania, USA
Investigating the Utility of Baseline Imaging in Early-Stage Mycosis Fungoides: A retrospective analysis
Sarah M. Gonzalez, Department of Dermatology, Dartmouth-Hitchcock Medical Center, USA

15:00

Understanding Patient Experiences and Quality of Life in Cutaneous T-Cell Lymphoma Through a Patient Education and Support Meeting
Brigit A. Lapolla, Columbia University, New York, USA
Central nervous system involvement in mycosis fungoides and Sézary syndrome: multicenter series of 24 cases from French Cutaneous Lymphoma Study Group
Marie Beylot-Barry, University Hospital Bordeaux, France

15:10

Q&A / Panel Discussion Q&A / Panel Discussion
15:30 – 16:30

Session 8A – More Than Skin Deep: Patient Perspectives In Cutaneous Lymphoma
Montreal Ballroom

Chair: Julia Scarisbrick
Co-Chairs: Elise Olsen, Constanze Jonak

Learning Objectives

At the end of this session, participants will be able to:

1. Identify strategies to incorporate patient perspectives into clinical decision-making and care planning.
2. Recognize the importance of patient-centered care in the management of cutaneous lymphoma and how this may elevate patient quality of life.

15:30

Introduction – Julia Scarisbrick

15:35

Core Concepts to Assess Health-Related Quality of Life in Patients with Mycosis Fungoides and Sézary Syndrome in Clinical Trials: Results of two Electronic Delphi Rounds
Jenny J. Park, Department of Dermatology, University of Washington, USA

15:45

Improved symptoms and health-related quality of life in patients with mycosis fungoides and Sézary syndrome treated with mogamulizumab in the PROSPER study
Julia J. Scarisbrick, Centre for Rare Diseases, University Hospital of Birmingham, United Kingdom

15:55

Using Skindex-29 and targeted instruments to assess the impact of patient factors on quality-of-life and diagnosis understanding over time in cutaneous lymphomas
Alyssa Wu, City of Hope, USA

16:10 – 17:20 

Session 8B – Evolving Perspectives in Cutaneous T-Cell Lymphoma: From Traditional Histopathology to Advanced Diagnostic and Biological Insights
Fortifications Ballroom 

Chair: Emmilia Hodak
Co-Chairs: Melissa Pulitzer, Kevin Pehr

Patient-Reported Quality of Life Outcomes Following Extracorporeal Photopheresis for Cutaneous T-Cell Lymphoma and Graft-Versus-Host Disease.
Manda D. Mootien, Guys and St. Thomas, United Kingdom
 16:05

Learning Objectives

At the end of this session, participants will be able to:

1. Understand new techniques for diagnosis of cutaneous T-cell lymphoma
2. Appreciate the complexity of cutaneous T- cell lymphoma and where diagnoses may overlap.

16:10

Introduction – Emmilia Hodak

16:15

Beyond Disease Control: Holistic Needs Assessment in Patients with Cutaneous Lymphoma in a Tertiary Skin Lymphoma Clinic
Amirtha Rajasekaran, University Hospitals Birmingham NHS Foundation Trust, United Kingdom
Reduced diversity in CTCL intratumoral microbiome is associated with JAK/STAT pathway alterations, non-European ancestry, and poor survival.
Paola Ghione, Memorial Sloan Kettering Cancer Center, USA

16:25

Q&A / Panel Discussion Cytotoxic hyperactivation paired with vascular dysfunction and tissue hypoxia mediates lesion self-destruction in lymphomatoid papulosis
Patrick Brunner, Department of Dermatology, Icahn School of Medicine at Mount Sinai, USA

16:35

Multi-Harmonic Imaging-Based Automated Recognition of Cutaneous T-Cell Lymphoma
Yi-Chien Tsai, Department of Dermatology and Venereology, University Hospital Centre (CHUV) and University of Lausanne (UNIL), Switzerland

16:45

Geographic and temporal validation of a histopathology-based diagnostic prediction model for risk-stratified triage of early-stage mycosis fungoides
Anne M. Schrader, Department of Pathology, Leiden University Medical Center, Netherlands

16:55

Cutaneous anaplastic large cell lymphoma (ALCL): Clinical, histopathologic, molecular review of 13 cases of primary cutaneous ALCL & cutaneous involvement of systemic ALCL
Emma Johnson, Mayo Clinic, Rochester, MN, USA

17:05

Overlap: mycosis fungoides / Sezary syndrome and inflammatory dermatosis, a case series.
Giorgio Alberto Croci, University of Milan, Italy

17:15

Q&A / Panel Discussion
17:30–18:30

POSTER SESSION WALK IN EXHIBIT HALL
Grande Place (8th Floor)
 

Chair and Poster Walk Leader: Pablo Ortiz-Romero

18:30–19:30 Canadian Skin Lymphoma Network Board Meeting
[by Invitation]
Fortifications

 

19:00-22:30

 

GALA RECEPTION AND DINNER
Ticket purchase required
Montreal Ballroom

 

Saturday, June 27
07:00–15:00 REGISTRATION
07:15 – 08:15 CONTINENTAL BREAKFAST AND POSTER VIEWING IN EXHIBIT HALL
Grande Place (8th Floor)
08:15 – 10:15

Session 9A – Old Treatments Performing New Tricks
Montreal Ballroom 

Chair: Francine Foss
Co-Chairs: Alain Rook, David Roberge

Session 9B – Patient Case Viewing and Discussions
Fortifications  Ballroom 

Chair: Ivan Litvinov
Co-Chairs: Ellen Kim, Jasmine Zain, Amrita Goyal

Learning Objectives

At the end of this session, participants will be able to:

1. To describe the efficacy and adverse effects of available therapeutics in the treatment of cutaneous lymphomas
2. To understand the spectrum of use of some older therapeutics in the management of cutaneous T and B cell lymphomas

At the end of this session, participants will be able to:
08:15 Introduction – Francine Foss Introduction – Ivan Litvinov
08:20 Long-term outcomes after allogeneic stem cell transplantation for cutaneous T-cell lymphoma
Samer A. Srour, The University of Texas MD Anderson Cancer Center, USA
Clinical Spectrum and Diagnostic Challenges of Cutaneous T-Cell Lymphomas in Ghana: a Retrospective Analysis from a Tertiary Referral Center in Accra (2015–2024)
Prince Agyemang, Eastern Regional Hospital, Ghana
08:30 Exploring the curative potential of allo-SCT in Cutaneous T-Cell Lymphoma
Julia J. Scarisbrick, University Hospitals Birmingham NHS Foundation Trust, United Kingdom
Ocular Mycosis Fungoides: A Single Center Case Series
Rishabh Lohray, Baylor College of Medicine, USA
08:40 Interferon Alfa Lives on: Real-World Use and Safety of Pegylated Interferon Alfa-2a in Cutaneous T-Cell Lymphoma
Christina Cruz, University of Pennsylvania, USA
Recurrent bulky tumors in a post-allogeneic stem cell transplanted Mycosis Fungoides patient cleared with a single dose of pembrolizumab
Lauren Spadt, University of Virginia School of Medicine, USA
08:50 Clinical Outcomes and Durability of Localized Radiation Therapy Versus Topical Steroids in Stage IA Mycosis Fungoides
Sarah J. Lange, Dartmouth Geisel School of Medicine, USA
New recalcitrant perigenital tumor in the setting of otherwise well-controlled Sezary syndrome
Katherine De Jong, Northwestern University, USA
09:00 Systematic Review and Institutional Case Series of Intralesional Rituximab for the treatment of Primary Cutaneous B-cell Lymphoma
Jori Hardin, University of Calgary, Division of Dermatology, Canada
Epidermotropic cutaneous T-cell lymphoma with gamma delta immunophenotype: Four instructive cases
Jacqueline Junkins-Hopkins, Geisinger Medical Center, USA
09:10 Hands and Feet Radiation Therapy for Cutaneous T-cell lymphoma
Ahmadou B. El Alaoui, Memorial Sloan Kettering Cancer Center, USA
Merkel Cell Carcinoma: A Cutaneous B-Cell Lymphoma in Disguise?
Ivan V. Litvinov, St. Mary’s Hospital Centre, McGill University, Canada
09:20 The Therapeutic Potential of PDE4 Inhibitors in Mycosis Fungoides and Sézary Syndrome: A Brief In Vitro Study
Teruyoshi Hisamoto, International University of Health and Welfare Hospital, Japan
Clinical Warburg Effect in a Primary Cutaneous Lymphoma
Emmanuella Guenova, Department of Translational Immunodermatology, Kepler University Hospital, Johannes Kepler University, Austria
09:30

Management of advanced mycosis fungoides and Sézary syndrome: international consensus recommendations from EHA, EORTC-CLTG, ISCL and EBMT
Pietro Quaglino, Department of Medical Sciences, Section of Dermatology, University of Turin,  Italy

Cutaneous CD8+ Cytotoxic Gamma-Delta T-cell Lymphoma Mimicking Angioedema
Eleanor B. Ostroff, Northwestern University Feinberg School of Medicine, USA
09:40

Linking CTCL cell biology with response to mogamulizumab for therapy optimization and identification of resistance mechanisms
Jan P. Nicolay, University Medical Center Mannheim, Germany

Vulvar and Perianal CD8-Positive Lymphomatoid Papulosis: A Case for Interdisciplinary Management of Unknown Genital Lesions
Sarah M. Gonzalez, Department of Dermatology, Dartmouth-Hitchcock Medical Center, USA
09:50

Mapping the Spatial Immune Landscape in Sezary Syndrome: Insights into Moderate and Progressive Prognoses
Marie Chevalier, Leiden University Medical Center, Leiden, Netherlands

CD8+ Primary Cutaneous Peripheral T-Cell Lymphoma in a 64-Year-Old Male: A Case Report and Diagnostic Insight
Karla Katrina T. Cajigal, Jose R. Reyes Memorial Medical Center Department of Dermatology, Philippines
10:00 Q&A / Panel Discussion Q&A / Panel Discussion
 10:15-10:55 MORNING BREAK AND POSTER VIEWING IN EXHIBIT HALL
Grande Place (8th Floor)
10:55 – 12:25

Session 10 – Challenging Assumptions in Cutaneous Lymphomas: A Debate Series
Montreal Ballroom 

Chairs: H. Miles Prince, Maarten Vermeer, Evangelia Papadavid

Learning Objectives

At the end of this session, participants will be able to:

1. Clarify evolving diagnostic boundaries in CTCL by examining expert debates on SPTCL classification, Sézary syndrome presentations, and pediatric CTCL evaluation.
2. Apply current evidence to differentiate challenging CTCL presentations, including blood involvement without erythroderma, in order to improve diagnostic accuracy and clinical decision‑making.
3. Integrate prognostic indicators into the management of early‑stage MF and evaluate whether treatment strategies should be modified at disease onset.

10:55 Introduction – TBC
11:00 Should SPTCL be classified as a lymphoma? – Michael Girardi vs Joan Guitart
11:20 Pediatric CTCL: Are we underdiagnosing or overdiagnosing? – Chalid Assaf
11:40 Should we treat early MF with poor prognostic indicators differently from the onset? – Jade Cury Martins vs. Maarten Vermeer
12:00 Sézary syndrome without erythroderma as the initial presentation of a T-cell lymphoma. Is it a Mycosis fungoides debuting with stage B2 – Emmilia Hodak, vs. Pablo Ortiz-Romero
12:20 Final Q&A
12:25 – 12:55 ISCL Assembly Meeting and Awards
Montreal Ballroom
12:55–13:55 LUNCH AND POSTER VIEWING IN EXHIBIT HALL
Montreal Ballroom Foyer
14:05 – 15:30

Session 11 – Best of Congress
Montreal Ballroom

Primary Chairs: Emmanuela Guenova, Jose Sanchez, Chalid Assaf

Learning Objectives

At the end of this session, participants will be able to:

1. Summarize key advances and high-impact findings presented across multiple sessions of the Congress, as identified by expert Co-Chairs.
2. Integrate selected best-practice insights into clinical decision-making and future research directions in cutaneous lymphomas.

14:05 Introduction – TBC
14:10-14:35 3 best sessions – Emmanuela Guenova
14:35-15:00 3 best sessions – Jose Sanchez
15:00-15:25 3 best sessions – Chalid Assaf
15:25 Q&A / Panel Discussion
15:30 Closing Remarks

6th World Congress of Cutaneous Lymphomas Starting:

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6th World Congress of Cutaneous Lymphomas

Call for Abstracts

The 6th World Congress of Cutaneous Lymphomas (6WCCL) will be held June 25–27, 2026, at the Westin Montréal in Montréal, Canada. This premier international meeting will showcase the latest advances in the research, diagnosis, and management of cutaneous lymphomas. The Scientific Committee invites you to submit abstracts for consideration as oral or poster presentations. Including opportunities for young investigators. Submissions from across the global community of experts are encouraged, with acceptance based on scientific merit. Join us in contributing to a dynamic program that will make this our most impactful Congress yet.

Abstract submissions will be accepted for the following topics:

  1. Classification / Epidemiology / Prognostic Factors
  2. Therapeutics / Preclinical Studies
  3. Pathology / Biomarkers / microenvironment
  4. Cutaneous Lymphoma International Consortium – PROCLIPI Studies
  5. Quality of Life / Patient Reported Outcomes
  6. Challenging Cases of Cutaneous Lymphomas

IMPORTANT DATES:

6WCCL Online Abstract System opens:

Abstract Submission Deadline:

Abstract Notification: 

Late-breaking Abstract System opens: 

Presenting Author Registration Deadline:

Late-breaking Abstract Deadline: 

Presentation at the 6WCCL: 

Thursday, October 16, 2025

Friday, January 23, 2026 – now closed

Thursday, February 26, 2026

Thursday, February 26, 2026

Tuesday, March 17, 2026

Monday, March 23, 2026 – now closed

June 25-27, 2026

6th World Congress of Cutaneous Lymphomas

 CME Accreditation

RCPSC Accreditation Statement

The Royal College of Physicians and Surgeons of Canada This event is an Accredited Group Learning Activity (Section 1) as defined by the Maintenance of Certification program of the Royal College of Physicians and Surgeons of Canada, and approved by the Canadian Dermatology Association. You may claim a maximum number of 18.25 hours.

AMA Accreditation Statement

Through an agreement between the Royal College of Physicians and Surgeons of Canada and the American Medical Association, physicians may convert Royal College MOC credits to AMA PRA Category 1 Credits™. More information on the process to convert Royal College MOC credit to AMA credit.

European Union Medical Specialists Accreditation Statement

Live educational activities recognized by the Royal College of Physicians and Surgeons of Canada as Accredited Group Learning Activities (Section 1) are deemed by the European Union of Medical Specialists (UEMS) eligible for ECMEC®.

German Medical Association Accreditation Statement

Through an agreement between the Royal College of Physicians and Surgeons of Canada and the German Medical Association, Royal College MOC Section 1 credits are deemed to be substantively equivalent to GMA CPD credits.

6th World Congress of Cutaneous Lymphomas Starting:

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6th World Congress of Cutaneous Lymphomas

Contact Us!

For more information, please contact the Congress Secretariat, Simply Eventful Management